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Kramer J: Intervertebral Disc Disease: Causes, Diagnosis, Treatment, and Prophylaxis

Alternative antimalarial agents, often used in HCQ-resistant disease, include quinacrine and chloroquine

Therefore, inhibition of GSDME cleavage or/and its pore formation activity can potently inhibit liposome leakage and pyroptosis

Besides, vitamin B12, methylcobalamin has neurological effect indirectly, methylation of myelin shelth phospholipids via 5-methyltetrahydroxyfolate-homocystine methyltransferase (MTR) reaction