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Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcription factor upregulating the antioxidant response element (ARE)-mediated expression of antioxidant and detoxifying enzymes, and the Nrf2-antioxidant pathway is critical in host defense against acute lung injury (ALI) 24

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Mutat Res 548:107116 Macfadyen AJ, Reiter C, Zhuang Y, Beckman JS (1999) A novel superoxide dismutase-based trap for peroxynitrite used to detect entry of peroxynitrite into erythrocyte ghosts

When stored at -20C, the active ingredients will remain effective for at least 2 months, but the integrity of the liposomes may be damaged when frozen for more than 2 months