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The procedure of animal husbandry and all experimental protocols in rats and monkeys were approved by the Institutional Animal Care and Use Committee (IACUC) in the Korea Institute of Toxicology (Approval No

Furthermore, the mtDNA nt7778 G-to-T polymorphism does not exacerbate cerulein-induced AP in mice but may accelerate the progression of autoimmune-like lesions after tissue damage, particularly in older mice, indicating its potential role for the polymorphism in autoimmune disease susceptibility following pancreatic injury (157)

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Patients between the ages of 18 and 65 will receive IV therapy as an elective treatment