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The most usual symptom of GERD is heartburn, i.e

A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma

The pKa of the Cys 34 albumin thiol group is relatively low (~5) in comparison to the pKa of other low molecular weight aminothiols present in the plasma (8.5-8.9 for Cys and GSH, respectively) (105)