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MicroRNA fingerprints during human megakaryocytopoiesis

These include:5 MAPK/ERK signaling pathway : The MAPK/EKR signaling pathway is important for cell proliferation, cell differentiation, and the elimination of damaged cells, among other things.6 Proapoptotic proteins : Proapoptotic proteins help trigger apoptosis, or programmed cell death, which is critical for removing damaged or unwanted cells (e.g., cancer cells)

However, in the background of the wild-type enzyme no slight increase in basal activity was observed with these mutations 49 , and as such, we believe that altered oligomerisation should be considered as an aspect of rescue

Funding This research was supported by the National Natural Science Foundation of China (Grant No