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PGD2 has important physiologic effects including increasing vascular permeability, increasing intestinal permeability, increased venular permeability leading to flushing, bronchoconstriction, peripheral vasodilation, coronary and pulmonary artery vasoconstriction, enhancing histamine release from basophils, mucus hypersecretion, and inhibition of platelet aggregation

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Thats why I say its intriguing. Despite such logical reservations, I asked more than a dozen people I interviewed about side effects and heard only a few anecdotes about minor issues (in one case, stomach problems caused by an athlete screwing up dosages with a mislabeled vial)

Amphotericin B: side effects and toxicity