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The System Xc- which consists of light chain solute carrier family 7 member 11 (SLC7A11, xCT) and heavy chain solute carrier family 3 member 2 (SLC3A2) can transport glutamate (Glu) out of the cell and cystine into the cell

In contrast, when 2 and 5 Gy of X-irradiation was applied to the cells at 12 h after cell sorting, ZsG + cells exhibited a higher survival fraction than ZsG cells in MegTCCZsG (2 Gy, 0.54 0.02 and 0.79 0.06, p = 0.001

267 Moreover, genetic variants of mitophagy-related genes, such as ATG16L1 and immunity-related GTPase M ( IRGM ), disrupt mitochondrial quality control in IBD