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Consistent with the intent of an evidence-mapping scoping review, studies were selected based on translational relevance to musculoskeletal tissue healing, orthopaedic care, and perioperative decision-making

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A 43-amino acid synthetic peptide modeled after thymosin beta-4.- Reported to regulate actin dynamics via its LKKTETQ sequence, thereby influencing cellular migration and motility.- May also elevate microRNA-146a, which suppresses inflammatory pathways involving IRAK1 and TRAF6.- Preclinical studies point toward roles in wound contraction, tissue vascularization, and cardiac resilience under stress