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To determine whether or not these indole conjugates were formed in the course of extraction, solvent extracts from Arabidopsis foliage were incubated with recombinant At GSTU19

Front Pharmacol 12:624706 Thorn CF, Oshiro C, Marsh S, Hernandez-Boussard T, McLeod H, Klein TE, Altman RB (2011) Doxorubicin pathways: pharmacodynamics and adverse effects

We reasoned this route could exploit the Cys of the dipeptide to spontaneously couple with thioesters, analogous to native chemical ligation (NCL) 27,28