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In vitro studies demonstrated that AOD-9604 can directly stimulate lipolysis in isolated human adipocytes, though the potency was lower than native GH or synthetic lipolytic agents like epinephrine or isoproterenol

In mouse models, ALLO appears to increase neurogenesis, reduce amyloid deposition and improve performance on learning and memory tests, suggesting that it may serve as a regenerative therapeutic (197, 277279)

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On the one hand, ginsenoside Rg1 promotes the phosphorylation of Akt in the skeletal muscle, activating the PI3K/Akt pathway, facilitating the translocation of Nrf2 to the nucleus, and inducing the expression of antioxidant enzyme genes (111)