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doi: 10.1016/0024-3205(94)00796-9

However, it is critical to note that no human clinical trials have been published, and the safety and efficacy of 5-Amino-1MQ in humans remain unknown

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Homocysteine rises when there is not enough B12 in the cell fluid to support methylation, an important process where a methyl group is added to all sorts of molecules in the cell