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Intranasal delivery of iron chelators and management of central nervous system disease

For example, a clinical cohort study from NHANES 20172018 showed an inverse relationship between plasma vitamin C levels and high-sensitivity CRP (hs-CRP), a key marker of inflammation, with the most significant CRP reduction observed at plasma vitamin C levels up to 53.1 mol/L [59]

Many studies have shown that a deficit in glutathione is associated with psychopathology and clinical variables in schi-zophrenia.100101102 Mitochondrial dysfunction, which is closely associated with oxidative stress, is also associated with neurodegenerative change in schizophrenia

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