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Investigating the mechanisms of hallucinogen-induced visions using 3,4-methylenedioxyamphetamine (MDA): a randomized controlled trial in humans

This means: No dissolution step in stomach acid the compound is already in solution Direct mucosal absorption begins as soon as the liquid contacts the digestive lining Faster onset plasma glutathione levels rise more quickly than with capsules More consistent dose delivery less inter-individual variation in absorption The result: effervescent forms achieve 35x higher plasma glutathione levels than the same stated dose in standard capsule form

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Clin Exp Immunol 2006