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171: 2563 LP 2570

This knockdown also induces lactylation at the K73 site in ADP-ribosylation factor 1 (ARF1), which affects vesicle assembly and induces mitochondrial loading abnormalities, thereby blocking the release of mitochondria from astrocytes, ultimately exacerbating the extent of brain infarction in mice

Hb is thought to rapidly inactivate the NO signal by binding NO to the oxygenated Fe 2+ -heme metal center, which is followed by subsequent formation of metHb and nitrate with a high reaction constant of 68 10 7 M 1 s 1 (Eq