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GSSG accumulation induced cellular protein S -glutathionylation Post-translational protein S -glutathionylation occurs via the reversible addition of a proximal donor of glutathione to thiolate anions of cysteines in target proteins

ALC has been studied in various conditions including neurological and cognitive disorders such as Alzheimers, dementia, depression, neuropathies, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica

pH 4.8_0 h and pH 4.8_1 h, as the reference conditions, were used to normalize data

Advantages : vascular action, peripheral circulation support, sometimes prescribed in cases of lower limb arteritis or angina pectoris