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Introduction Diabetes mellitus (DM) is a worldwide chronic metabolic disorder characterized by high blood sugar and glucose in the urine due to inadequate insulin production or reduced insulin sensitivity in target cells [1]

doi:10.1096/fj.202101219RR Rangarajan S, Orujyan D, Rangchaikul P, Radwan MM

Mills et al., 2005)

These organoids can expand and differentiate into large numbers of functional hepatocytes in vitro , making them a potential alternative to liver transplantation or a biological patch for partially damaged liver tissue