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To further investigate the affected metabolic pathways, we performed enrichment analysis using the small molecule pathway database (SMPDB) (Fig

Results Synthesis of 1D228 The synthesis of 1D228 was performed according to methods in the patent with some modifications (Scheme 1)

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*Correspondence: Veronica Sanda Chedea [email protected] Maria Pop [email protected] This article was submitted to Cardiovascular Therapeutics, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers