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A total of 12,519 patients met the inclusion criteria for the primary dose analysis, and their clinical data on dose escalation and weight change during the first two years after semaglutide initiation were assessed in relation to cardiovascular outcomes during the subsequent two years

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Takeuchi D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T and Morishita R (2008) Alleviation of Abeta-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model