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Differentially expressed proteins (DEPs) between SUP and GRA groups were identified using a two-tailed Students t -test with BenjaminiHochberg correction for multiple testing

The remainder of the mice completed the 12-week dietary intervention, at which point they either remained on their respective diet for an additional 6 weeks or were switched to an equivalent diet with SG1002 (Sulfagenix, Cleveland, OH, USA) added at a concentration designed to deliver approximately 20 mg*kg -1 *day -1 for the subsequent 6 weeks

Certain enzymes known as Glu peptidases, including neprosin, have been found to effectively break down gluten peptides