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Acetate could directly activate the nucleotide-binding oligomerization domain containing 3 (NLRP3) inflammasome in mouse IECs, leading to the release of IL-18, and then promote the integrity of the intestinal barrier by activating the IL-18 receptor on mouse epithelial cells [141]

Future research about glutathione could entail creating delivery systems that include using nanoparticles or liposomes to increase absorption and bioavailability