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The family lachnospiraceae

Table 1 A summary compiling key studies and reviews that have described limb-related sensory symptomssuch as tingling, cramping, twisting, coldness, or sensory lossin the context of hyperglycemia or diabetic neuropathy

Mechanisms of resistance to, and toxicities resulting from, IGF-1R-targeted drugs are well-catalogued, and there is general appreciation of the fact that a lack of biomarker-based patient stratification was a limitation of previous clinical trials