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For instance, manuka honey restored the ability of metastatic colorectal cancer first-line drug 5-fluorouracil to abrogate resistance to apoptosis of cancer stem-like cells derived from the HCT-116 colon adenocarcinoma cell line by a pleiotropic mechanism involving the downregulation of IGF-1, IGF-2, IGF-1R, as well as other inhibitors of apoptosis, such as: inhibitors of apoptosis protein (IAP) family members survivin, livin, and XIAP

Qato DM, Wilder J, Schumm LP, Gillet V, Alexander GC

What ProHealth States: According to the company's product page, BPC-157 is marketed for support of tissue pathways, cellular processes, and biological functions based on preclinical research findings

In addition, mice were intraperitoneally injected with 20 mg/kg DDP once at day 1 for survival analysis