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For instance, one trial reported worsening motor symptoms in patients with early-stage PD, highlighting the complexity of iron-targeted therapy (52,60,124)

2010;143(7):1192e2

To understand why senescent cells are more prone than normal counterparts to undergo ferroptosis on GPX4 inhibition, we used fluorescence probes to analyse ROS, levels of Fe 2+ and lipid oxidation in senescent cells