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Inflamm Res 63(6):485494

once) to the mice causes significant liver damage and necrosis of cells as evidenced by the elevated serum hepatic enzymes alanine aminotransferase (ALT), aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GT) compared with normal group [3]

Functionalized PLGA nanoparticles, modified with ligands or peptides, demonstrated the ability to cross the BBB, enabling their use in neurological disorders like PD 116,117