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Figure 1 Differences in AM physiology between PWH, people on PrEP and HC To assess the correlation of epigenetic and transcriptomic features (i.e., accessible chromatin, H3K27me3, H3K27ac, H3K4me3, and RNA) with study group we performed a principal component analysis (PCA)

Manifestations of intestinal damage in HS When the core body temperature rises above 42 C, both baboons and mice can exhibit a large loss of intestinal epithelium, and severe damage occurs in both the small intestine and the large intestine, manifested as villous stroma broadening, focal necrosis, edema, and congestion

2.18 Statistical analysis Experiments were conducted in three independent biological replicates under standardized conditions

SOD, POD, CAT, and APX activities Superoxide dismutase (SOD