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[20] showed that overexpression of GPX3 could inhibit the proliferation of PCa cells and the size of xenograft tumors in vivo

Irisin inhibits lactate metabolism in MPTP-treated mice Previous studies have demonstrated a significant increase in lactate metabolism in MPTP-induced PD mouse models 8

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Similarly, in a model of allergic asthma, intranasal treatment with D-2-hydroxyglutarate suppressed allergic sensitization mediated by dendritic cells and promoted the activity of follicular regulatory T cells (84)