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Quercetin and apigenin exemplify clinically validated compounds with broad therapeutic applicability [223]

Moscow JA, Fairchild CR, Madden MJ, Ransom DT, Wieand HS, OBrien EE, et al

This response acts to delay pathology and suppresses ferroptosis, by promoting antioxidative factors, such as glutathione 159

Therefore, cholesterol accumulation and metabolic reprogramming in DCs play variable roles in orchestrating their functional specialization, providing novel mechanistic insights into DC-mediated modulation of immune homeostasis, autoimmune disorders, and anti-tumor immunity