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338 A-357300, which was subsequently developed, has shown anticancer activity in mouse models of cancer, sarcoma, and nervous system tumors, 339,340 and another candidate, METAPi A-800141, which was selected based on affinity selection based on mass spectrometry, has better selectivity and efficacy than A-357300

Chen, Y., Li, B., & Chen, B

This conversation also explores the difference between being sober and being emotionally well, why solitude can feel so threatening, how trauma can shape intimacy and attachment, and what it looks like to start choosing healing over validation

PLoS ONE 18 (10), e0287352 (2023)