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Bioavailability refers to how much of a substance actually reaches the bloodstream and the cells where it is needed

Front Mol Biosci 9:975582 Wiernicki B, Dubois H, Tyurina YY, Hassannia B, Bayir H, Kagan VE et al (2020) Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis

Since melatonin acts as an anti-inflammatory by modifying expression of NFkB and NLRP3 it may be a promising candidate as a radioprotective agent against oral mucositis [49]