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The monoclonal antibody CD147/HAb18 reduces inflammatory cytokines, inhibits MMPs, and alleviates synovitis as well as cartilage erosion in immuno-deficient mice engrafted with human rheumatoid synovium tissue and cartilage

They are preferred over others because they provide an array of features, including high permeability, biodegradability, good compatibility, good performance in allergen-specific immunotherapy, protection of nucleic acid components from nucleases, increased antibacterial actions, regulated medication release, improved cellular uptake, and improved nanoparticle stability [75]

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Neurotransmitters in cerebrospinal fluid reflect pathological activity