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Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells

moreover, the necessary dose and side effects can be significantly reduced [73,150,151]

Therefore, they got many kinds of selective inhibitors 90-94 in 2010 and 2011, and summarized the interaction of this type inhibitor as well, requiring the role of Glu61 and Cys99 in the inhibition of IKK for pyrazine type IKK inhibitors [186, 187]