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Statements Data availability statement The data presented in the study are deposited in the GitHub repository, available at and Ethics statement All animal experiments were conducted in strict accordance with the rules of animal care and use of Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences (IACUC Issue No.MD2023-01-10-01)

10.1016/j.clnu.2016.07.013 154 WangY.NieF.OuyangJ.WangX.MaX

Use in Pregnancy and Nursing: Exercise caution and consultation with healthcare professionals when used in pregnant or nursing women due to potential risks to the mother and infant