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Diabetes-driven gut dysbiosis acts as a key amplifier, exacerbating systemic metabolic and immune perturbations

Based on permeation studies, the diameter of the selectivity filter was estimated to be 2.63 , and the inner pore of the channel was projected to have a diameter of 8 ( In the nervous system, GIRK channels regulate neuronal excitability through GIRK-mediated self-inhibition (Scanziani, 2000