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Description

Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

Sebelipase alfa over 52 weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency

This neuroadaptive state can contribute to the development of tolerance, dependence, and withdrawal symptoms, further complicating the recovery process for individuals with AUDs (Bhandari et al