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The study was registered (ClinicalTrials.gov Identifier: NCT02118883) and conducted in accordance and compliance with Good Clinical Practice and the Declaration of Helsinki

AOD-9604 received FDA GRAS (Generally Recognized As Safe) status as a food ingredient in 2007, but this is not drug approval

Thus Affimer K6 has a 10-fold higher affinity for KRAS than Abd-7 7 , the strongest-binding small molecule with a K D of 51 nM (c.f 750 nM for BI-2852 11 and 1.1 mM for DCAI 6 and 340 M for compound 13 8 )

[8] No significant drug-drug interactions with NAD+ Injection have been identified in the medical literature to date