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Supporting Source Trimethylglycine (TMG) What it does: Acts as a methyl donor, supporting DNA repair and liver detoxification

As shown in the summary table in section XII.B.7 of the preamble of this proposed rule, we estimate a total information collection burden increase for 11 PCHs of 188 hours at a cost of $4,088 annually associated with our proposed policies and updated burden estimates beginning with the FY 2027 program year compared to our currently approved information collection burden estimates

The involvement of MLKL in APAP-induced liver injury is questionable however, since two studies found that MLKL knockout mice were not protected [74,132]

In cats, psyllium acts as a gentle bulk-forming laxative , absorbing water and forming a gel that helps normalise stool consistency