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Pharmacological blockers of GPX4 have been demonstrated to trigger ferroptosis in B cells within the context of central-nervous-system mitochondrial diseases (Kahn-Kirby et al., 2019)

In patients with end-stage renal disease, increased circulating oxalate was not only associated with CVD events, but also with aggravated dyslipidemia (increased triglycerides and VLDL-cholesterol, and decreased HDL-cholesterol) and proatherogenic cytokines and chemokines (IL-6, TNF, and monocyte chemoattractant protein-1) (254)

Pang Y, Cheng M, Chen M, et al

This CMS initiative is consistent with key components that were detailed in CMSs Framework for Health Equity, the agencys 10-year plan to remedy systemic barriers to equity so that every one [CMS] serve[s] has a fair and just opportunity to attain their optimal health regardless of race, ethnicity, disability, sexual orientation, gender identity, socioeconomic status, geography, preferred language, or other factors that affect access to care and health outcomes.[1] This post outlines the changes being proposed by CMS, as well as highlights opportunities where providers should consider preparing and submitting comments