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Sleep can become more challenging as we age, but maintaining good sleep hygiene habits exposing yourself to sunlight upon waking and keeping your bedroom dark, cool, and free from technology at night can help mitigate sleep issues

Stem cell activity, the Wnt/-catenin signalling pathway, hormonal regulation, neurovascular control, extracellular matrix dynamics, the influence of the microbiota, inflammatory pathways, epigenetic regulation, and environmental factors are some of the important elements

Of course we cant know if this imposed reduced frequency had any impact however the word pernicious springs to mind

These hormones are, in turn, able to modulate mitochondrial activities