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doi:10.1016/S0076-6879(71)18006-8

These promising results are still awaiting confirmation in human in vivo models (107)

Downregulating MYCN in IMR-5/75 decreased caspase activation for both treatments, while inducing MYCN expression in SH-SY5Y/MYCN increased caspase activation, although the differences were not statistically significant ( Figure 4D )