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Peer review Peer review information Nature Chemical Biology thanks Rudi Fasan and the other, anonymous reviewer(s) for their contribution to the peer review of this work

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Briefly, mostly ring-stage parasites were incubated at 0.2% initial parasitemia and 1% hematocrit with a range of CB-27 concentrations at 37C for 72 h in 96-well plates as previously described (Ekland et al., 2011)