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Mitochondria represent attractive targets for phototoxic agents due to their susceptibility to oxidative stress and their crucial roles in regulating intracellular Ca 2+ levels, oxidative stress, survival/apoptotic signaling pathway, cellular differentiation and the cell cycle 98

You want a needle that is: Wide gauge (18G to 21G): Draws water quickly and passes through rubber stoppers easily Longer (1 inch to 1.5 inches): Reaches the bottom of the vial to draw water completely On a standard Luer-lock syringe (1 mL to 3 mL): Gives you enough volume and a secure needle connection You use this needle once per reconstitution session (which might be once per month or once every few weeks depending on your vial size and dose)