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The characteristics of the basolateral sugar transporter, identified as GLUT2 , are similar to those of other sugar transport systems in erythrocytes, fibroblasts, and adipocytes

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For example, this promotes fibrogenesis in the liver worsening the course of underlying hepatic disorders, and a similar worsening effect is observed on the course of other chronic disorders apparently not directly linked to iron homeostasis such as metabolic and cardiovascular disorders (Pietrangelo, 2016)