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Metabolism rate Most people metabolize alcohol at 0.015% BAC per hour, but this can range from 0.01% to 0.03% depending on genetics, liver health, and regular alcohol use

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Given that EtOH-induced mitochondrial dysfunction and ER stress are intimately involved in the pathogenesis of ALD, future studies to examine these pathways under the current experimental setting will provide important mechanistic information underlying the protection seen in GCLM KO mice