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I recommend: at least 2,000 mcg (g) cyanocobalamin once each week, ideally as a chewable, sublingual, or liquid supplement taken on an empty stomach or at least 50 mcg daily of supplemental cyanocobalamin or a serving of B12-fortified foods three times a day, each containing at least 190 percent of the Daily Value listed on the nutrition facts label Those over 65 years of age should take at least 1,000 mcg (g) cyanocobalamin every day

doi: 10.1002/bjs.10770 58 MemehKRuhleBVaghaiwallaTKaplanEKeutgenXAngelosP

Because of this, oral vitamin B12 is considered to be safe even at high doses

Researchers often study it in lab work on Nicotinamide N-Methyltransferase (NNMT)