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Int J Mol Sci 24(21):15536 Markina AA, Kazanskaya RB, Timoshina JA, Zavialov VA, Abaimov DA, Volnova AB, Fedorova TN, Gainetdinov RR, Lopachev AV (2023) Na+, K+-ATPase and cardiotonic steroids in models of Dopaminergic System pathologies

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More specifically, in vitro studies have shown that RES reduces inflammation in UC by decreasing IL-1 levels and increasing IL-11 production, primarily through the modulation of the Nrf2 pathway in both TNF- challenged Caco-2 cells and patient tissue samples [408]