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Second, exercise induces significant skeletal muscle remodeling, enhancing metabolic capacity and enabling the efficient utilization of glucose and fatty acids as energy sources [173, 174]

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(NB: These variations in attachments are important as often an injury to the hamstring can implicate the medical collateral ligament or the posterolateral corner of the knee) Causes There are many different factors that can predispose an athlete to a tear: Poor flexibility of the muscles Reduced or side-to-side differences in strength of hamstrings Increased neural tightness, often arising from the lower back Inadequate warm up Fatigue Poor biomechanics or running pattern Return to activity prematurely following previous injury Grade of Tear Grade 1 Usually a mild strain where cramping or tightness may be felt

Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease