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Claims that MIC B12 injections deliver a specific weekly pound count are marketing, not data and where such losses occur, they are attributable to the caloric deficit and the accountability structure of the program, not the injection

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No dose-ranging studies have established safety margins, optimal administration routes, or duration of treatment

As found here, PAT is a noncompetitive TGR inhibitor with a K i value in the low nanomolar range, showing that PAT is by three orders of magnitude a better inhibitor of TGR than of PFK, which has an IC 50 of 16 M [65]