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doi: 10.1007/s00405-019-05346-3 8 ArguedasA.KvaernerK.LieseJ.SchilderA.PeltonS

T H 17 cells are involved in host defence against extracellular pathogens, but also contribute to the pathogenesis of immune-mediated diseases such as MS

The raised flap is entirely dependent on blood flow through small vessels at its base, and any factor that compromises oxygen delivery (anaemia being a major one) puts the flap at risk