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What are the Potential Effects of DSIP Peptides

Oxygen and glucose deprivation (OGD) mimics ischemic stroke-induced hyper-permeability of HBMECs due to internalization of VE-cadherin and is dependent on activation of the RhoA/Rock pathway (Chen et al., 2+ in BECs and pericytes and was correlated with the loss of TJs, AJs, increased BBB permeability, and pericyte death (Imai et al., 2020)

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Tissue Repair and Cellular Regeneration BPC-157, a stable gastric pentadecapeptide, has been shown in animal studies to accelerate healing in muscle, tendon, and nerve tissue by enhancing angiogenesis and modulating growth factor expression