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Tolerability (animal only): Reported as well tolerated in limited rodent studies an animal observation, not a human safety finding

That fatty acid chain, specifically a C20 fatty diacid, is what gives tirzepatide its extended half-life in the body

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The relative risk (RR) of all-cause dementia in subjects with baseline plasma PC DHA levels in the upper quartile compared with subjects with levels in the lower 3 quartiles was estimated after controlling for potential confounding factors